Samarium Diiodide Mediated Reactions in Total Synthesis
Top Cited Papers
- 9 September 2009
- journal article
- review article
- Published by Wiley in Angewandte Chemie
- Vol. 48 (39), 7140-7165
- https://doi.org/10.1002/anie.200902151
Abstract
Introduced by Henri Kagan more than three decades ago, samarium diiodide (SmI2) has found increasing application in chemical synthesis. This single‐electron reducing agent has been particularly useful in CC bond formations, including those found in total synthesis endeavors. This Review highlights selected applications of SmI2 in total synthesis, with special emphasis on novel transformations and mechanistic considerations. The examples discussed are both illustrative of the power of this reagent in the construction of complex molecules and inspirational for the design of synthetic strategies toward such targets, both natural and designed.This publication has 211 references indexed in Scilit:
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