Fast acoustic tweezers for the two-dimensional manipulation of individual particles in microfluidic channels
- 10 September 2012
- journal article
- research article
- Published by AIP Publishing in Applied Physics Letters
- Vol. 101 (11)
- https://doi.org/10.1063/1.4751348
Abstract
This paper presents a microfluidic device that implements standing surface acoustic waves in order to handle single cells, droplets, and generally particles. The particles are moved in a very controlled manner by the two-dimensional drifting of a standing wave array, using a slight frequency modulation of two ultrasound emitters around their resonance. These acoustic tweezers allow any type of motion at velocities up to few x 10 mm/s, while the device transparency is adapted for optical studies. The possibility of automation provides a critical step in the development of lab-on-a-chip cell sorters and it should find applications in biology, chemistry, and engineering domains. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4751348]Keywords
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