Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model
- 30 April 2013
- journal article
- Published by Elsevier BV in Clinical Immunology
- Vol. 147 (1), 27-37
- https://doi.org/10.1016/j.clim.2013.02.004
Abstract
No abstract availableKeywords
Funding Information
- NIH (AI 38425, AI 70535, AI 72115)
- Veterans Affairs Career Development Award-2
- American Asthma Foundation
This publication has 45 references indexed in Scilit:
- ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6Proceedings of the National Academy of Sciences of the United States of America, 2012
- The updated biology of hypoxia-inducible factorThe EMBO Journal, 2012
- Hypoxia-Inducible Factors in Physiology and MedicineCell, 2012
- Hypoxia Inducible Factor promotes murine allergic airway inflammation and is increased in asthma and rhinitisAllergy, 2011
- Refractory asthma in the UK: cross-sectional findings from a UK multicentre registryThorax, 2010
- Hypoxia modulates human eosinophil functionClinical and Molecular Allergy, 2010
- Interdependence of hypoxic and innate immune responsesNature Reviews Immunology, 2009
- IL-4 Is Proangiogenic in the Lung under Hypoxic ConditionsThe Journal of Immunology, 2009
- Collagen-related gene and protein expression changes in the lung in response to chronic hypoxiaBiomechanics and Modeling in Mechanobiology, 2008
- Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research ProgramJournal of Allergy and Clinical Immunology, 2007