The Clinical Meaning of Intramammary Lymph Nodes
- 8 October 2012
- journal article
- Published by S. Karger AG in Oncology
- Vol. 84 (1), 1-5
- https://doi.org/10.1159/000340016
Abstract
The clinical meaning of intramammary lymph nodes (iMLNs) is uncertain. We wanted to describe the clinical characteristics and understand the implications of iMLNs detected by sentinel LN biopsy (SLNB). We reviewed the clinical, radiological and pathological records of women diagnosed with invasive carcinoma of the breast at the Samsung Medical Center between January 2001 and January 2011. A total of 69 patients were identified, and SLNB was performed in 31 patients. Of the 69 patients included in the study, 22 (31.9%) had metastases in iMLNs. The presence of lymphovascular invasion and the number of axillary LN metastases were associated with iMLN metastasis. Of the 31 patients who underwent SLNB, there were no cases with axillary LN metastasis when axillary SLNB was negative, even in cases of iMLN-positive patients. Of the 10 patients in whom intramammary SLNs (iMSLNs) were detected during SLNB, 8 patients without iMLN metastases were also negative for axillary LNs. Patients with metastatic iMLNs had more aggressive cancers with lymphovascular invasion and increased axillary LN metastases. When iMSLN was detected by SLNB, performing of axillary dissection could be determined by the status of the iMSLN itself.Keywords
This publication has 15 references indexed in Scilit:
- Intramammary lymph node metastasis predicts poorer survival in breast cancer patientsSurgical Oncology, 2010
- The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNMAnnals of Surgical Oncology, 2010
- Implication of an Intramammary Sentinel Lymph Node in Breast Cancer: Is This a True Sentinel Node? A Case ReportBreast Care, 2010
- Surgical management of the axilla: do intramammary nodes matter?The American Journal of Surgery, 2009
- Intramammary Sentinel Lymph Nodes: What is the Clinical Significance?Annals of Surgical Oncology, 2008
- When Sentinel Lymph Node is IntramammaryAnnals of Surgical Oncology, 2007
- Intramammary lymph nodes and breast cancer: a marker for disease severity, or just another lymph node?The American Journal of Surgery, 2006
- Intramammary lymph node metastases are an independent predictor of poor outcome in patients with breast carcinomaCancer, 2004
- Intramammary lymph nodes.Journal of Clinical Pathology, 1992
- Intramammary lymph nodesCancer, 1983