Alanine-scanning Mutations in Domain 4 of Anthrax Toxin Protective Antigen Reveal Residues Important for Binding to the Cellular Receptor and to a Neutralizing Monoclonal Antibody
Open Access
- 1 August 2003
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 278 (33), 30936-30944
- https://doi.org/10.1074/jbc.m301154200
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Human capillary morphogenesis protein 2 functions as an anthrax toxin receptorProceedings of the National Academy of Sciences, 2003
- Cell Surface Tumor Endothelium Marker 8 Cytoplasmic Tail-independent Anthrax Toxin Binding, Proteolytic Processing, Oligomer Formation, and InternalizationJournal of Biological Chemistry, 2003
- Anthrax toxin triggers endocytosis of its receptor via a lipid raft–mediated clathrin-dependent processThe Journal of cell biology, 2003
- The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigenProceedings of the National Academy of Sciences, 2002
- Identification of the cellular receptor for anthrax toxinNature, 2001
- Genes Expressed in Human Tumor EndotheliumScience, 2000
- Crystal structure of the anthrax toxin protective antigenNature, 1997
- pH‐dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigenMolecular Microbiology, 1993
- Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin.Proceedings of the National Academy of Sciences, 1992
- Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers.Proceedings of the National Academy of Sciences of the United States of America, 1989