Pentacyclic triterpenoids and their cytotoxicity from the stem bark ofStyrax japonica S. et Z
- 1 March 2004
- journal article
- research article
- Published by Springer Science and Business Media LLC in Archives of Pharmacal Research
- Vol. 27 (3), 283-286
- https://doi.org/10.1007/bf02980060
Abstract
The methylene chloride soluble fraction of MeOH extract from the stem bark ofStyrax japonica S. et Z. (Styracaceae) showed significant cytotoxicity by SRB method against five human tumor cell lines. Four known pentacyclic triterpenoids, oleanolic aldehyde acetate (1), erythrodiol-3-acetate (2), euphorginol (3), and anhydrosophoradiol-3-acetate (4) were isolated by activity-guided fractionation. Their structures were determined by chemical and spectral analysis. Compounds1–4 were isolated fromS. japonica for the first time.Keywords
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