Quality of life of people living with HIV/AIDS and on highly active antiretroviral therapy in Ethiopia
- 1 April 2010
- journal article
- Published by Taylor & Francis Ltd in African Journal of AIDS Research
- Vol. 9 (1), 31-40
- https://doi.org/10.2989/16085906.2010.484560
Abstract
The Amharic version of the Short Form-36 Health Survey (SF-36) was used to measure quality of life among patients on highly active antiretroviral therapy (HAART) at selected governmental hospitals in central and southern Ethiopia. The study was cross-sectional and used SF-36-specific software for automatic scoring of the form's scales and dimensions. Pearson bivariate correlations showed moderate correlation between the SF-36 scales, ranging from 0.2673 between 'general health' and 'vitality,' to 0.8583 between 'role physical' and 'role emotional.' Cronbach's-αwas >0.70 for six out of eight multi-item scales, with values ranging from 0.6500 to 0.8860 for all scales, thus indicating good internal reliability of the Amharic version of the SF-36. The independent variables shown to positively affect mean scores were: duration of treatment, CD4 cell count, and adherence to doses of antiretrovirals. Participants treated for >12 months had higher mean scores for all domains than those who had been treated for ≤12 months. Likewise, those with a CD4 cell count >200 cells/mm(3) had better mean scores for all scales except 'social functioning' and 'mental health' than those with counts ≤200. Participants adhering to treatment (in the last 15 days, according to self-report) had better mean scores for all scales except 'role physical,' 'bodily pain' and 'vitality' in comparison to those who were not adherent. The findings suggest that the Amharic version of the SF-36 is a valid and reliable health survey instrument for use in Ethiopia to assess the quality of life of people living with HIV/AIDS on HAART.Keywords
This publication has 25 references indexed in Scilit:
- Validity and Reliability of the Short Form- 36 Items Questionnaire as a Measure of Quality of Life in Elderly Iranian PopulationAmerican Journal of Applied Sciences, 2006
- Adherence to MedicationThe New England Journal of Medicine, 2005
- Quality of life in HIV-infected individuals receiving antiretroviral therapy is related to adherenceAIDS Care, 2005
- Measuring quality of life among HIV-infected women using a culturally adapted questionnaire in Rakai district, UgandaAIDS Care, 2004
- Chinese SF-36 Health Survey: translation, cultural adaptation, validation, and normalisationJournal of Epidemiology and Community Health, 2003
- Assessing quality of life in women living with HIV infectionAIDS Care, 2002
- Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG Adherence InstrumentsAIDS Care, 2000
- Cross-Validation of Item Selection and Scoring for the SF-12 Health Survey in Nine Countries: Results from the IQOLA ProjectJournal of Clinical Epidemiology, 1998
- Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus InfectionThe New England Journal of Medicine, 1998
- Human Aging: Usual and SuccessfulScience, 1987