Diffuse optical correlation tomography of cerebral blood flow during cortical spreading depression in rat brain
Open Access
- 6 February 2006
- journal article
- Published by Optica Publishing Group in Optics Express
- Vol. 14 (3), 1125-1144
- https://doi.org/10.1364/oe.14.001125
Abstract
Diffuse optical correlation methods were adapted for three-dimensional (3D) tomography of cerebral blood flow (CBF) in small animal models. The image reconstruction was optimized using a noise model for diffuse correlation tomography which enabled better data selection and regularization. The tomographic approach was demonstrated with simulated data and during in-vivo cortical spreading depression (CSD) in rat brain. Three-dimensional images of CBF were obtained through intact skull in tissues deep (∼ 4 mm) below the skull surface.This publication has 56 references indexed in Scilit:
- Pronounced Hypoperfusion during Spreading Depression in Mouse CortexJournal of Cerebral Blood Flow & Metabolism, 2004
- Spatiotemporal Quantification of Cerebral Blood Flow during Functional Activation in Rat Somatosensory Cortex using Laser-Speckle FlowmetryJournal of Cerebral Blood Flow & Metabolism, 2004
- Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activationOptics Letters, 2003
- Dynamic Imaging of Cerebral Blood Flow Using Laser SpeckleJournal of Cerebral Blood Flow & Metabolism, 2001
- Scanning Laser-Doppler Flowmetry of Rat Cerebral Circulation during Cortical Spreading DepressionJournal of Vascular Research, 2000
- Perfusion magnetic resonance imaging with continuous arterial spin labeling: methods and clinical applications in the central nervous systemEuropean Journal of Radiology, 1999
- Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): A steady‐state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fractionMagnetic Resonance in Medicine, 1998
- Spectroscopy and Imaging with Diffusing LightPhysics Today, 1995
- Magnetic resonance imaging of perfusion using spin inversion of arterial water.Proceedings of the National Academy of Sciences of the United States of America, 1992
- Quantitative Measurement of Regional Cerebral Blood Flow and Oxygen Metabolism in Man Using 15O and Positron Emission TomographyJournal of Computer Assisted Tomography, 1980