Locked-in syndrome: a review of 139 cases.
- 1 July 1986
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Stroke
- Vol. 17 (4), 758-764
- https://doi.org/10.1161/01.str.17.4.758
Abstract
Etiology, clinical manifestations and outcome were reviewed in 139 cases of "locked-in syndrome." Six cases were reported from our center and the remaining 133 cases were taken from a review of the literature. The results of this review emphasized the necessity for a comprehensive program of pulmonary management in this population. Furthermore, an effective system of communication for the patient is considered essential in the management of the "locked-in" state. Reported mortality in the cases reviewed was 60%. Overall, the prognosis for survival and recovery was found to be better in the group of patients whose syndrome was nonvascular in origin than those with a vascular etiology. Functional recovery was generally good in those patients with a vascular etiology who survived beyond 4 months while recovery occurred earlier and more completely in the nonvascular group. Thus, a program of intensive rehabilitation should be considered early in both groups in order to assist each patient in attaining the highest level of function possible as recovery progresses.This publication has 53 references indexed in Scilit:
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