GENETIC POLYMORPHISM IN HUMAN GLYCINE-RICH BETA-GLYCOPROTEIN

Abstract
Extensive polymorphism of glycine-rich ß-glycoprotein (GBG) was found in human sera. In all instances, GBG consisted of at least five components on electrophoresis. Patterns were such that they provided evidence for four alleles (at a locus designated Gb) which were expressed as autosomal codominant traits. GbS and GbF were found in all populations but with different frequencies, GbF1 was found in Negroes, and GbS1 was found in Caucasians.