Thallium-201 for myocardial imaging. Relation of thallium-201 to regional myocardial perfusion.
- 1 April 1975
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 51 (4), 641-645
- https://doi.org/10.1161/01.cir.51.4.641
Abstract
Following intravenous administration, the myocardial concentration of tracer thallium-201, potassium-43, and rubidium-81 were determined in mice; thallium was present in the greatest concentration in the myocardium (2.08% compared 1.25% for potassium and 1.15% for rubidium at 10 minutes). The regional myocardial distribution of thallium-201 was determined in dogs under conditions of normal flow, and total occlusion, and compared with potassium-43 (r=0.97). The regional distribution of thallium-201 was compared to microspheres under conditions of partial occlusion and reactive hyperemia (r=0.97). Thallium-201 was evaluated in a series of phantom scans, which demonstrated that the low energy X-ray of thallium was suitable for imaging. These results suggest that thallium-201 can be used for the evaluation of the distribution of regional myocardial perfusion.Keywords
This publication has 4 references indexed in Scilit:
- Rubidium-81: A New Myocardial Scanning AgentRadiology, 1974
- Noninvasive Evaluation of Regional Myocardial Perfusion with Potassium 43Radiology, 1973
- Noninvasive Regional Myocardial Perfusion with Radioactive PotassiumNew England Journal of Medicine, 1973
- Thallium activation of the (Na+-K+)-activated ATPase of rabbit kidneyBiochimica et Biophysica Acta (BBA) - Enzymology, 1968