The Biology and Chemistry of Fertilization
- 30 January 1987
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 235 (4788), 553-560
- https://doi.org/10.1126/science.3027891
Abstract
Fertilization of eggs by sperm, the means by which sexual reproduction takes place in nearly all multicellular organisms, is fundamental to the maintenance of life. In both mammals and nonmammals, the pathway that leads to fusion of an egg with a single sperm consists of many steps that occur in a compulsory order. These steps include species-specific cellular recognition, intracellular and intercellular membrane fusions, and enzyme-catalyzed modifications of cellular investments. In several instances, the molecular mechanisms that underlie these events during mammalian fertilization are beginning to be revealed.Keywords
This publication has 79 references indexed in Scilit:
- Membrane fusion: from liposomes to biological membranesTrends in Biochemical Sciences, 1984
- Assembly of the fertilization membrane of the sea urchin: Isolation of a divalent cation-dependent intermediate and its crosslinking in vitroCell, 1982
- Molecular Approaches to The Study of FertilizationAnnual Review of Biochemistry, 1981
- Isolation of a high molecular weight glycoconjugate derived from the surface of S purpuratus eggs that is implicated in sperm adhesionJournal of Supramolecular Structure and Cellular Biochemistry, 1981
- Sequential biochemical and morphological events during assembly of the fertilization membrane of the sea urchinCell, 1977
- Changes in the topography of the sea urchin egg after fertilization.The Journal of cell biology, 1976
- Primary gamete binding: Quantitative determination of its specificity in echinoid fertilizationExperimental Cell Research, 1976
- Protease released from sea urchin eggs at fertilization alters the vitelline layer and aids in preventing polyspermyExperimental Cell Research, 1973
- Induction of Zona Reaction in Golden Hamster Eggs by Cortical Granule MaterialNature, 1971
- Proteolytic Reaction of Mammalian Spermatozoa on Gelatin MembranesScience, 1970