Multiple roles of HDAC inhibition in neurodegenerative conditions
Top Cited Papers
- 30 November 2009
- journal article
- review article
- Published by Elsevier BV in Trends in Neurosciences
- Vol. 32 (11), 591-601
- https://doi.org/10.1016/j.tins.2009.06.002
Abstract
No abstract availableKeywords
This publication has 106 references indexed in Scilit:
- HDAC2 negatively regulates memory formation and synaptic plasticityNature, 2009
- Acetylation Targets Mutant Huntingtin to Autophagosomes for DegradationCell, 2009
- Deregulation of HDAC1 by p25/Cdk5 in NeurotoxicityNeuron, 2008
- Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse modelNeuroscience, 2008
- Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neuronsInternational Journal of Neuropsychopharmacology, 2008
- Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosisNature, 2008
- Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disordersCurrent Opinion in Pharmacology, 2008
- Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicityNeuroscience, 2007
- SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosisThe EMBO Journal, 2007
- HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPSNature, 2007