The cell surface: the stage for matrix metalloproteinase regulation of migration
- 11 September 2002
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Cell Biology
- Vol. 14 (5), 624-632
- https://doi.org/10.1016/s0955-0674(02)00363-0
Abstract
Matrix metalloproteinases are important for the turnover of extracellular matrix in tissue. Recent studies have expanded their roles well beyond extracellular matrix degradation — they also cleave many growth factors, cytokines and cell adhesion molecules in the extracellular milieu, modulating their functions irreversibly. In particular, some matrix metalloproteinases that associate with the cell surface have arisen as intriguing regulators of cellular functions, including migration.Keywords
This publication has 66 references indexed in Scilit:
- Matrix metalloproteinases: a tail of a frog that became a princeNature Reviews Molecular Cell Biology, 2002
- Processing of Integrin αv Subunit by Membrane Type 1 Matrix Metalloproteinase Stimulates Migration of Breast Carcinoma Cells on Vitronectin and Enhances Tyrosine Phosphorylation of Focal Adhesion KinaseJournal of Biological Chemistry, 2002
- An Alternative Processing of Integrin αv Subunit in Tumor Cells by Membrane Type-1 Matrix MetalloproteinasePublished by Elsevier BV ,2002
- Pro-collagenase-1 (Matrix Metalloproteinase-1) Binds the α2β1 Integrin upon Release from Keratinocytes Migrating on Type I CollagenPublished by Elsevier BV ,2001
- Structural Analysis of the α2 Integrin I Domain/Procollagenase-1 (Matrix Metalloproteinase-1) InteractionPublished by Elsevier BV ,2001
- Mutation Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP): THE ROLE OF THE CYTOPLASMIC TAIL CYS574, THE ACTIVE SITE GLU240, AND FURIN CLEAVAGE MOTIFS IN OLIGOMERIZATION, PROCESSING, AND SELF-PROTEOLYSIS OF MT1-MMP EXPRESSED IN BREAST CARCINOMA CELLSPublished by Elsevier BV ,2001
- CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migrationOncogene, 1999
- Membrane Type 1-Matrix Metalloproteinase Is Involved in the Formation of Hepatocyte Growth Factor/Scatter Factor-Induced Branching Tubules in Madin-Darby Canine Kidney Epithelial CellsBiochemical and Biophysical Research Communications, 1998
- High Affinity Binding of Latent Matrix Metalloproteinase-9 to the α2(IV) Chain of Collagen IVPublished by Elsevier BV ,1998
- Activation of a recombinant membrane type 1‐matrix metalloproteinase (MT1‐MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)‐2FEBS Letters, 1996