Regional P-Glycoprotein Activity and Inhibition at the Human Blood–Brain Barrier as Imaged by Positron Emission Tomography
- 24 March 2010
- journal article
- research article
- Published by Wiley in Cancer Cell
- Vol. 87 (5), 579-585
- https://doi.org/10.1038/clpt.2010.11
Abstract
We used positron emission tomography (PET) to evaluate the contribution of P-glycoprotein (P-gp), present at the human blood–brain barrier (BBB), to regional drug distribution in the brain. Eleven he...Keywords
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