Making diazomethane accessible for R&D and industry: generation and direct conversion in a continuous micro-reactor set-up

Abstract

Micro-reaction technology offers a safe way to deliver diazomethane on demand both on the R&D and the industrially relevant scale, including in situ conversion to the desired product to avoid handling and storage of explosive diazomethane solutions, thus making this potent compound accessible for the pharmaceutical and fine chemical sector.