Pyruvate Kinase M2 Increases Angiogenesis, Neurogenesis, and Functional Recovery Mediated by Upregulation of STAT3 and Focal Adhesion Kinase Activities After Ischemic Stroke in Adult Mice
- 4 June 2018
- journal article
- research article
- Published by Elsevier BV in Neurotherapeutics
- Vol. 15 (3), 770-784
- https://doi.org/10.1007/s13311-018-0635-2
Abstract
No abstract availableFunding Information
- National Institute of Neurological Disorders and Stroke (NS085568, NS091585, NS073378)
- U.S. Department of Veterans Affairs (RX000666)
This publication has 45 references indexed in Scilit:
- The Role of Pyruvate Kinase M2 in Cancer MetabolismBrain Pathology, 2015
- A genetic perspective on glucose consumption in the cerebral cortex during human developmentDiabetes, Obesity and Metabolism, 2014
- Pyruvate Kinase M2 in Blood Circulation Facilitates Tumor Growth by Promoting AngiogenesisOnline Journal of Public Health Informatics, 2014
- Pyruvate Kinase M2: Regulatory Circuits and Potential for Therapeutic InterventionCurrent Pharmaceutical Design, 2014
- Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein KinaseMolecular Cell, 2012
- Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ3Blood, 2011
- Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growthProceedings of the National Academy of Sciences of the United States of America, 2011
- Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating CellsScience, 2010
- Integrins in angiogenesis and lymphangiogenesisNature Reviews Cancer, 2008
- Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesisOncogene, 2002