Ligand-independent Thrombopoietin Mutant Receptor Requires Cell Surface Localization for Endogenous Activity
Open Access
- 1 May 2009
- journal article
- Published by Elsevier BV
- Vol. 284 (18), 11781-11791
- https://doi.org/10.1074/jbc.m808703200
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosisBlood, 2007
- New thrombopoietic growth factorsBlood, 2007
- MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patientsPublished by American Society of Hematology ,2006
- MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid MetaplasiaPLoS Medicine, 2006
- Janus Kinases Affect Thrombopoietin Receptor Cell Surface Localization and StabilityJournal of Biological Chemistry, 2005
- Internal and external autocrine VEGF/KDR loops regulate survival of subsets of acute leukemia through distinct signaling pathwaysBlood, 2004
- Revisiting the Fluid Mosaic Model of MembranesScience, 1995
- Thrombocytopenia in c-mpl-deficient miceScience, 1994
- Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietinNature, 1994
- Transformation by v- sis Occurs by an Internal Autoactivation MechanismScience, 1989