Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration
- 10 January 2006
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology
- Vol. 66 (1), 102-104
- https://doi.org/10.1212/01.wnl.0000191395.69438.12
Abstract
The authors used voxel-based morphometry to compare the patterns of brain atrophy in two variants of pathologically confirmed frontotemporal lobar degeneration (FTLD): FTLD with motor neuron disease (FTLD-MND) and FTLD with ubiquitin-only-immunoreactive neuronal changes (FTLD-U). Patterns of atrophy were distinct and different from each other. A localized pattern of frontal lobe atrophy was found in FTLD-MND with a more widespread pattern of atrophy affecting the frontal and temporal lobes in FTLD-U.Keywords
This publication has 9 references indexed in Scilit:
- Magnetic Resonance Imaging Signatures of Tissue Pathology in Frontotemporal DementiaArchives of Neurology, 2005
- Comparison of different methodological implementations of voxel-based morphometry in neurodegenerative diseaseNeuroImage, 2005
- Pattern of glucose hypometabolism in frontotemporal dementia with motor neuron diseaseNeurology, 2005
- Hippocampal Sclerosis and Ubiquitin-Positive Inclusions in Dementia Lacking Distinctive HistopathologyDementia and Geriatric Cognitive Disorders, 2004
- Frontotemporal lobar degeneration and ubiquitin immunohistochemistryNeuropathology and Applied Neurobiology, 2004
- Volumetric analysis reveals corticospinal tract degeneration and extramotor involvement in ALSNeurology, 2001
- Clinical and Pathological Diagnosis of Frontotemporal DementiaArchives of Neurology, 2001
- Frontotemporal lobar degenerationNeurology, 1998
- A Short Test of Mental Status: Description and Preliminary ResultsMayo Clinic Proceedings, 1987