Periodontal disease and perinatal outcomes: a case‐control study
- 24 November 2006
- journal article
- research article
- Published by Wiley in Journal of Clinical Periodontology
- Vol. 34 (1), 31-39
- https://doi.org/10.1111/j.1600-051x.2006.01012.x
Abstract
Our aim was to measure the association of maternal periodontitis with low birth weight (LBW), pre-term LBW, and intra-uterine growth restriction. An inclusive case-control design including subjects examined for periodontitis through attachment loss, information on perinatal outcomes and general health. Data were analysed through conditional logistic regression. Cases (n=304) and controls (n=611) had similar prevalence and severity of periodontitis, defined as at least three sites, in different teeth, with loss of three or more millimetres of clinical attachment level. Several factors were associated with the outcome, but the crude odds ratio for periodontitis was not significant. Odds ratio were 0.93 [95% confidence interval (CI): 0.63-1.41] for LBW and 0.92 (95% CI:0.54-1.57) for pre-term LBW in the presence of periodontitis, after adjustment for maternal age, previous pregnancies, pre-natal care, smoking, previous low birth or premature birth and other medical conditions, on a hierarchical model. Results do not support the hypothesis of association observed in previous studies after appropriate controlling for confounding variables. Negative peri-natal outcomes are better explained by determinants other than periodontal health. This study adds to the growing body of literature on the relationship between periodontal diseases and systemic health.Keywords
This publication has 38 references indexed in Scilit:
- Doença periodontal materna como fator associado ao baixo peso ao nascerRevista de Saúde Pública, 2005
- Is there an association between periodontal disease, prematurity and low birth weight? A population‐based studyJournal of Clinical Periodontology, 2005
- Association between periodontitis and low birth weight: a case–control studyJournal of Clinical Periodontology, 2005
- The increase in very-low-birthweight infants in Germany: artefact or reality?Paediatric and Perinatal Epidemiology, 2002
- The Association Between Porphyromonas gingivalis‐Specific Maternal Serum IgG and Low Birth WeightThe Journal of Periodontology, 2001
- The East London Study of Maternal Chronic Periodontal Disease and Preterm Low Birth Weight Infants: Study Design and Prevalence DataAnnals of Periodontology, 1998
- Situação de saúde da criança em área da região sul do Brasil, 1980-1992: tendências temporais e distribuição espacialRevista de Saúde Pública, 1994
- STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENTThe Lancet, 1986
- The Contribution of Low Birth Weight to Infant Mortality and Childhood MorbidityThe New England Journal of Medicine, 1985
- A simplified method for diagnosis of gestational age in the newborn infantThe Journal of Pediatrics, 1978