Potentiation of Amyotrophic Lateral Sclerosis (ALS)-associated TDP-43 Aggregation by the Proteasome-targeting Factor, Ubiquilin 1
Open Access
- 1 March 2009
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 284 (12), 8083-8092
- https://doi.org/10.1074/jbc.m808064200
Abstract
No abstract availableKeywords
This publication has 65 references indexed in Scilit:
- Autophagy in neurodegeneration and developmentBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2008
- Two German Kindreds With Familial Amyotrophic Lateral Sclerosis Due to TARDBP MutationsArchives of Neurology, 2008
- Novel targets for Huntington's disease in an mTOR-independent autophagy pathwayNature Chemical Biology, 2008
- TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expressionProceedings of the National Academy of Sciences of the United States of America, 2008
- TDP-43: a novel neurodegenerative proteinopathyCurrent Opinion in Neurobiology, 2007
- Studies of the Role of Ubiquitination in the Interaction of Ubiquilin with the Loop and Carboxyl Terminal Regions of Presenilin-2Biochemistry, 2007
- Small molecules enhance autophagy and reduce toxicity in Huntington's disease modelsNature Chemical Biology, 2007
- The UBL domain of PLIC‐1 regulates aggresome formationEMBO Reports, 2006
- Dimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilinsBiochemical Journal, 2006
- Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosisNature, 1993