Predictors of mortality in HIV-1 exposed uninfected post-neonatal infants at the Kenyatta National Hospital, Nairobi

Abstract

Objectives: To identify potential predictors of mortality, to determine mortality rate and to identify prevalent causes of death in a cohort of HIV-l exposed uninfected infants. Design: Prospective cohort study. Setting: Kenyatta National Hospital, Nairobi, Kenya. Subjects: Three hundred and fifty one HIV-l exposed uninfected post-neonatal infants who survived to one year of age. Results: Sixteen infants died (post-neonatal mortality rate of 47/l000 live births), 14 (88%) before six months of age. The most frequently identified medical conditions at death included bronchopneumonia, diarrhoea and failure to thrive. In multivariate analysis, prematurity (RR=10.5, 95%CI 3.8-29.1, pEast African Medical Journal Vol. 82(9) 2005: 447-451