Off-Line Learning and the Primary Motor Cortex
Open Access
- 6 July 2005
- journal article
- research article
- Published by Society for Neuroscience in Journal of Neuroscience
- Vol. 25 (27), 6372-6378
- https://doi.org/10.1523/jneurosci.1851-05.2005
Abstract
We are all familiar with acquiring skills during practice, but skill can also continue to develop between practice sessions. These “off-line” improvements are frequently supported by sleep, but they can be time dependent when a skill is acquired unintentionally. The magnitude of these over-day and overnight improvements is similar, suggesting that a similar mechanism may support both types of off-line improvements. However, here we show that disruption of the primary motor cortex with repetitive transcranial magnetic stimulation blocks off-line improvements over the day but not overnight. This suggests that a memory may be rescued overnight and subsequently enhanced or that different aspects of a skill, with differential dependencies on the primary motor cortex, are enhanced over day and overnight. Off-line improvements of similar magnitude are not supported by similar mechanisms; instead, the mechanisms engaged may depend on brain state.This publication has 31 references indexed in Scilit:
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