A new consecutive three-component oxazole synthesis by an amidation–coupling–cycloisomerization (ACCI) sequence
- 29 September 2006
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 46,p. 4817-4819
- https://doi.org/10.1039/b610839c
Abstract
A novel consecutive three-component synthesis of 1-(hetero)aryl-2-(2-(hetero)aryl-oxazol-5-yl) ethanones starting from propargyl amine and acid chlorides, both for amidation and cross-coupling, is based upon an amidation–coupling–cycloisomerization (ACCI) sequence.Keywords
This publication has 29 references indexed in Scilit:
- Artificial Neural Networks and Linear Discriminant Analysis: A Valuable Combination in the Selection of New Antibacterial CompoundsJournal of Chemical Information and Computer Sciences, 2004
- Iterative Oxazole Assembly via α‐Chloroglycinates: Total Synthesis of (−)‐Muscoride AAngewandte Chemie, 2003
- OxazolesPublished by Elsevier BV ,1996
- Synthetic Studies of Biologically Active Marine CyclopeptidesChemical Reviews, 1995
- Total Synthesis of the Enantiomer of the Antiviral Marine Natural Product Hennoxazole AJournal of the American Chemical Society, 1995
- A new synthesis of highly functionalized oxazolesThe Journal of Organic Chemistry, 1993
- An efficient synthesis of ethyl 5-oxazoleacetatesThe Journal of Organic Chemistry, 1990
- Oxazoles and Oxazolines in Organic SynthesisPublished by Wiley ,1986
- Chemistry of oxazolesChemical Reviews, 1975
- Mechanism of the Robinson-Gabriel synthesis of oxazolesThe Journal of Organic Chemistry, 1973