Embryonal rhabdomyosarcoma of the uterine cervix in a 47‐year‐old woman
- 16 March 2011
- journal article
- case report
- Published by Wiley in Journal of Obstetrics and Gynaecology Research
- Vol. 37 (7), 940-946
- https://doi.org/10.1111/j.1447-0756.2010.01449.x
Abstract
Embryonal rhabdomyosarcoma (RMS) of the female genital tract usually occurs in the vagina during childhood. The uterine cervix as a primary site is rare, but is more frequent until the second decade of life. It usually has a good prognosis and the treatment is based on multidrug chemotherapy, radiotherapy and surgery. RMS accounts for <5% of all adult soft tissue sarcomas. Previous reports that included all primary sites showed a poorer five‐year disease specific survival for adults with RMS when compared to the pediatric population. This difference has been attributed to a higher proportion of adverse prognostic clinical and pathological factors, and to inadequate treatment given to adults with RMS. A total of 115 patients with cervical embryonal RMS have previously been described; however, only 10 cases were reported in women older than 40 years. We present a 47‐year‐old woman treated with radical hysterectomy followed by adjuvant chemotherapy and review the current literature.Keywords
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