Primary cutaneous cryptococcosis in immunocompetent and immunocompromised hosts
Open Access
- 1 January 2003
- journal article
- case report
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 41 (3), 177-188
- https://doi.org/10.1080/1369378031000137224
Abstract
A case of primary cutaneous cryptococcal infection is presented and cases of primary cutaneous cryptococcosis in normal and immunocompromised hosts are reviewed. Cutaneous cryptococcosis can occur from local inoculation or dissemination from a distant site of infection. Risk factors associated with development of primary cutaneous cryptococcosis are those which affect cell-mediated immunity, such as corticosteroid usage, solid organ transplantation, sarcoidosis and immunosuppression. The cutaneous manifestations of cryptococcosis are protean and may mimic other cutaneous diseases. Patients with a diagnosis of cryptococcosis from a skin biopsy or culture should undergo evaluation to exclude disseminated disease and an evaluation of cell-mediated immunity. Although some patients do well without antifungal therapy, these patients cannot be discerned prospectively and therefore antifungal therapy appears warranted in all patients with localized disease. Choice of therapy depends on the extent of disease and immunocompetence of the host.Keywords
This publication has 41 references indexed in Scilit:
- Characterization of Intestinal Disease Associated with Human Immunodeficiency Virus Infection and Response to Antiretroviral TherapyThe Journal of Infectious Diseases, 1999
- Effect of the human immunodeficiency virus epidemic on mortality from opportunistic infections in the United States in 1993.The Journal of Infectious Diseases, 1997
- Primary cutaneous cryptococcosis in an immunocompetent pigeon keeperClinical and Experimental Dermatology, 1997
- Stevens-Johnson syndrome associated with topical nitrogen mustard therapyJournal of the American Academy of Dermatology, 1997
- Primary cutaneous cryptococcosis and Cryptococcus neoformans serotype DClinical and Experimental Dermatology, 1995
- Management of Injuries Caused by Cryptococcus neoformans-Contaminated NeedlesClinical Infectious Diseases, 1994
- Cutaneous cryptococcal infection without immunodeficiencyClinical and Experimental Dermatology, 1994
- PRIMARY CUTANEOUS CRYPTOCOCCOSIS IN EGYPTInternational Journal of Dermatology, 1975
- Primary Cutaneous CryptococcosisDermatology, 1971
- CUTANEOUS CRYPTOCOCCOSIS.British Journal of Dermatology, 1962