Micro-Optical Sectioning Tomography to Obtain a High-Resolution Atlas of the Mouse Brain
- 3 December 2010
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 330 (6009), 1404-1408
- https://doi.org/10.1126/science.1191776
Abstract
Better Brain Maps: A high-resolution atlas of the complete neuronal connectivity in a whole brain should fundamentally advance our understanding of the organization and function of animal nervous systems. Now, A. Li. et al. (p. 1404 , published online 4 November) describe an automated system, micro-optical sectioning tomography, that allowed three-dimensional mapping of the morphology and spatial location of neurons and traces of neurites in a whole, intact mouse brain.Keywords
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