Epigenetic effects in eukaryotic gene expression
- 1 January 1994
- journal article
- review article
- Published by Wiley in Developmental Genetics
- Vol. 15 (6), 458-462
- https://doi.org/10.1002/dvg.1020150603
Abstract
In the broadest terms, epigenetic phenomena in eukaryotes depend on the interaction of alleles or repeated sequences or on the mitotic inheritance of chromatin states or methylation patterns. One of the most exciting aspects of the study of epigenetic phenomena is the insight that can be gained into the structure and assembly of higher‐order chromatin structures, an important subject that has proved refractory to current biochemical methodologies. Rapid progress in the study of gene inactivation in fungi, plants, and invertebrates will provide new hypotheses to be tested in mammals.Keywords
This publication has 29 references indexed in Scilit:
- Role for DNA methylation in genomic imprintingNature, 1993
- Cytosine methylation The pros and cons of DNA methylationCurrent Biology, 1993
- Genomic Imprinting in Plants: Parental Effects and Trans-Inactivation PhenomenaAnnual Review of Plant Physiology and Plant Molecular Biology, 1993
- Epigenetic variation as a consequence of homology-dependent gene interactions in transgenic plantsSeminars in Developmental Biology, 1993
- Regulating genes by packaging domains: bits of heterochromatin in euchromatin?Trends in Genetics, 1993
- Targeted mutation of the DNA methyltransferase gene results in embryonic lethalityCell, 1992
- X-chromosome inactivation and cell memoryTrends in Genetics, 1992
- Trans-sensing effects from Drosophila to humansCell, 1991
- DNA methylation: evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotesPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1990
- The Theory and Application of a New Method of Detecting Chromosomal Rearrangements in Drosophila melanogasterThe American Naturalist, 1954