Screening Asymptomatic Adolescent Men for Chlamydia trachomatis in School-Based Health Centers Using Urine-Based Nucleic Acid Amplification Tests
- 1 November 2008
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Sexually Transmitted Diseases
- Vol. 35 (11), S19-S23
- https://doi.org/10.1097/olq.0b013e3181844f10
Abstract
Urine-based screening for Chlamydia trachomatis using highly sensitive and specific nucleic acid amplification tests offers a unique opportunity to screen men attending school-based health centers. As part of a large multicenter chlamydia screening project in men, 1434 students were enrolled; 1090 in high schools in Baltimore and 344 middle and high-school students in Denver. Students were screened for chlamydia using urine-based nucleic acid amplification tests at well adolescent visits, acute care visits, or visits for other reasons, such as sports physicals. A self-administered survey to ascertain sexual risk behaviors was used. Data were analyzed separately for Baltimore and Denver, with univariate and multivariate logistic regression analysis. The overall prevalence in asymptomatic adolescent men was 6.8% (7.5% in Baltimore and 4.7% in Denver, P = n.s.). Students in Denver were older, more racially diverse, and more likely to have had intercourse in the previous 2 months than students in Baltimore. Students in Baltimore were more likely than those in Denver to have used a condom at last intercourse with casual and main partners. Among men in Denver but not Baltimore, condom use at last intercourse with both casual (OR 0.15, 95% CI, 0.03, 0.78) and main partners (OR 0.30, 95% CI, 0.10, 0.91) was protective against infection. The only risk factor for CT infection in Baltimore students was age (OR 1.47, 95% CI, 1.23, 1.75). In multivariate analysis that included age (as a continuous variable), race, history of an STI, any sex partner in the last 2 months, >1 sex partner in the past 12 months, a new partner in the last 2 months, and condom use with last main and last casual partner, age (adjusted odds ratio 1.34, 95% CI, 1.11, 1.62) and black race (adjusted odds ratio 2.37, 95% CI, 1.21, 4.63) were the only variables associated with testing chlamydia positive. School-based health centers are important venues in which to perform urine-based screening for chlamydia in sexually active, asymptomatic males, especially in high prevalence communities, and such screening provides the opportunity to identify and treat substantial numbers of chlamydia infections.Keywords
This publication has 23 references indexed in Scilit:
- Screening of males for Chlamydia trachomatis and Neisseria gonorrhoeae infections at STD clinics in three US cities — Indianapolis, New Orleans, SeattleInternational Journal of STD & AIDS, 2004
- Feasibility and Short-Term Impact of Linked Education and Urine Screening Interventions for Chlamydia and Gonorrhea in Male Army RecruitsSexually Transmitted Diseases, 2004
- Prevalence of Chlamydial and Gonococcal Infections Among Young Adults in the United StatesJAMA, 2004
- Cost-Effectiveness Analysis of Screening Adolescent Males for Chlamydia On Admission to DetentionSexually Transmitted Diseases, 2004
- Screening for sexually transmitted diseases during preparticipation sports examination of high school adolescentsJournal of Adolescent Health, 2003
- Risk Behaviors, Medical Care, and Chlamydial Infection Among Young Men in the United StatesAmerican Journal of Public Health, 2002
- Features ofChlamydia trachomatisandNeisseria gonorrhoeaeInfection in Male Army RecruitsThe Journal of Infectious Diseases, 2001
- Participation in a School-Based Sexually Transmitted Disease Screening ProgramSexually Transmitted Diseases, 2000
- Repeated School-based Screening for Sexually Transmitted Diseases: A Feasible Strategy for Reaching AdolescentsPublished by American Academy of Pediatrics (AAP) ,1999
- A School-based Chlamydia Control Program Using DNA Amplification TechnologyPediatrics, 1998