Trophoblastic invasion of human decidua from 8 to 18 weeks of pregnancy
- 1 January 1980
- journal article
- Published by Elsevier BV in Placenta
- Vol. 1 (1), 3-19
- https://doi.org/10.1016/s0143-4004(80)80012-9
Abstract
Trophoblastic invasion of the human decidua has been studied in 48 intact uteri with pregnancies ranging from 8 to 18 weeks after the last menstrual period. Some cytotrophoblast invades the distal segments of the spiral arteries to become endovascular while the rest diffusely infiltrates the decidua as an interstitial invader. The interstitial cytotrophoblast reaches the myometrium and gives rise to the characteristic placental bed giant cells. As the placental site enlarges the lateral spiral arteries come to lie obliquely; new openings into the intervillous space are created but this readjustment of the placental blood supply may cause focal superficial decidual necrosis. The physiological changes converting the spiral to the uteroplacental arteries are effected in the upper decidua by the action of endovascular and perivascular cytotrophoblast, whereas in the deeper decidua endovascular trophoblast is principally involved. Endometrial granulocytes aggregate in the region of maternal tissue degeneration with the heaviest trophoblast invasion but the role played by these cells in placentation is unknown.Keywords
This publication has 12 references indexed in Scilit:
- The demonstration of immunoglobulin in the metrial gland cells of the rat placentaReproduction, 1977
- Interactions of the trophoblast and maternal tissues in three closely related primate speciesAmerican Journal of Obstetrics and Gynecology, 1976
- THE ARTERIAL MIGRATION OF TROPHOBLAST IN THE UTERUS OF THE GOLDEN HAMSTER, MESOCRICETUS AURATUSReproduction, 1974
- The ultrastructure of the human placental bedThe Journal of Pathology, 1974
- Studies on the Function of the Kurloff CellInternational Archives of Allergy and Immunology, 1971
- The physiological response of the vessels of the placental bed to normal pregnancyThe Journal of Pathology and Bacteriology, 1967
- ZUM VERHALTEN DER SEKUNDÄREN WAND DER UTEROPLACENTARGEFÄSSE BEI DER DECIDUALEN REAKTIONCells Tissues Organs, 1964
- THE GIANT CELLS OF THE PREGNANT HUMAN UTERUSBJOG: An International Journal of Obstetrics and Gynaecology, 1960
- Über Auftreten und Verhalten der endometrialen Körnchenzellen im Verlauf der Schwangerschaft, im krankhaft veränderten Endometrium und außerhalb des Corpus uteriVirchows Archiv, 1957
- Über endometriale Granulocyten (endometriale Körnchenzellen)Klinische Wochenschrift, 1954