Nickel-Mediated Oxidative Fluorination for PET with Aqueous [18F] Fluoride
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- 12 October 2012
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 134 (42), 17456-17458
- https://doi.org/10.1021/ja3084797
Abstract
A one-step oxidative fluorination for carbon–fluorine bond formation from well-defined nickel complexes with oxidant and aqueous fluoride is presented, which enables a straightforward and practical 18F late-stage fluorination of complex small molecules with potential for PET imaging.Keywords
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