Small RNA guides for de novo DNA methylation in mammalian germ cells: Figure 1.
Open Access
- 15 April 2008
- journal article
- editorial
- Published by Cold Spring Harbor Laboratory in Genes & Development
- Vol. 22 (8), 970-975
- https://doi.org/10.1101/gad.1669408
Abstract
Germline genomic methylation is essential for gamete identity and integrity in mammals. The study by Kuramochi-Miyagawa and colleagues (908–917) in the previous issue of Genes & Development links the process of DNA methylation-dependent repression of retrotranspons with the presence of piwi-interacting RNAs (piRNAs) in fetal male germ cells undergoing de novo methylation.Keywords
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