Enhanced spectral discrimination through the exploitation of interface effects in photon dose data

Abstract

The convolution/superposition algorithm for computing dose from photon beams in radiation therapy planning requires knowledge of the energy spectrum. The algorithm can compute the dose for a polyenergetic beam as the weighted sum of the individual dose contributions from monoenergetic beams. In this study we exploit interface effects apparent in the dose distributions to discriminate among spectra of high energy photon beams. We have studied the sensitivity of the depth dose distribution to the energy components using a hypothetical beam for various field sizes and depths in water and water-lung-water media. Six theoretical spectra were simulated. We compared depth dose data from these spectra using three quantitative measures which are inherently free of normalization ambiguities: for homogeneous water, the ratio D20/D10 and a logarithmic derivative in the buildup region LD(build-up) and for inhomogeneous lung/water, the lung correction factor (CF). It was found that the ability of both the CF and the LD(build-up) tests to discriminate between the various theoretical spectra were superior to that of the D20/D10 test. This discriminating power of the CF test decreases with increasing field size due to restored electronic equilibrium. The CF test, though, has some advantages over the LD(build-up) test since it is less prone to electron contamination issues and numerical errors. A practical example with a 15 MV photon beam illustrates the process. Consequently, we suggest that as part of a beam-commissioning methodology, designated electronic disequilibrium test cases be implemented in unambiguously determining the correct energy spectrum to be used.