Comparison of clinical burden between patients with erosive hand osteoarthritis and inflammatory arthritis in symptomatic community-dwelling adults: the Keele clinical assessment studies
Open Access
- 17 September 2013
- journal article
- research article
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 52 (12), 2260-2267
- https://doi.org/10.1093/rheumatology/ket267
Abstract
Objective. To investigate in the general population the clinical impact of erosive OA in interphalangeal joints (IPJs) compared with symptomatic radiographic hand OA and inflammatory arthritis. Methods. Standardized assessments with hand radiographs were performed in participants of two population-based cohorts in North Staffordshire with hand symptoms lasting ≥1 day in the past month. Erosive OA was defined as the presence of an eroded or remodelled phase in ≥1 IPJ using the Verbruggen–Veys method. Radiographic hand OA was defined as the presence of ≥1 IPJ/first carpometacarpal joint with a Kellgren–Lawrence score of ≥2. Diagnoses of inflammatory arthritis were based on medical records. Hand pain and disability were assessed with the Australian/Canadian Hand Osteoarthritis Index (AUSCAN). Linear regression analyses were used to compare clinical determinants between groups and calculate mean differences with 95% CIs, adjusted for age and sex. Results. Of 1076 participants with hand symptoms [60% women, mean age 64.8 years (s.d. 8.3 years)]; 80 persons (7.4%) had erosive OA. The population prevalence of erosive OA in ≥1 IPJ was 2.4% (95% CI 1.8, 3.0). Persons with erosive OA reported more pain and disability than persons with symptomatic radiographic hand OA [adjusted mean difference 1.3 (95% CI 0.3, 2.3) and 2.3 (95% CI 0.4, 4.2), respectively]. Individuals with inflammatory arthritis (n = 44) reported more pain and disability than those with erosive OA [adjusted mean difference 1.7 (95% CI 0.05, 3.4) and 6.3 (95% CI 2.8, 9.9), respectively]. Conclusion. While erosive OA has a greater impact than symptomatic radiographic hand OA in the general population, it is not as severe in terms of hand pain and disability as inflammatory RA.Keywords
This publication has 26 references indexed in Scilit:
- Erosive hand osteoarthritis: its prevalence and clinical impact in the general population and symptomatic hand osteoarthritisAnnals Of The Rheumatic Diseases, 2011
- Health‐related quality of life in women with symptomatic hand osteoarthritis: A comparison with rheumatoid arthritis patients, healthy controls, and normative dataArthritis Care & Research, 2007
- The Clinical Assessment Study of the Hand (CAS-HA): a prospective study of musculoskeletal hand problems in the general populationBMC Musculoskeletal Disorders, 2007
- Measures of adult hand function: Arthritis Hand Function Test (AHFT), Grip Ability Test (GAT), Jebsen Test of Hand Function, and The Rheumatoid Hand Functional Disability Scale (The Duruöz Hand Index [DHI])Arthritis & Rheumatism, 2003
- SACRAH: a score for assessment and quantification of chronic rheumatic affections of the handsRheumatology, 2003
- The burden of musculoskeletal diseases in the general population of Spain: results from a national surveyAnnals Of The Rheumatic Diseases, 2001
- Reliability and validity testing of the Michigan Hand Outcomes QuestionnaireThe Journal of Hand Surgery, 1998
- A 12-Item Short-Form Health SurveyMedical Care, 1996
- AIMS2. The Content and Properties of a Revised and Expanded Arthritis Impact Measurement Scales Health Status QuestionnaireArthritis & Rheumatism, 1992
- Radiological Assessment of Osteo-ArthrosisAnnals Of The Rheumatic Diseases, 1957