Pemphigus associated with nail dystrophy
- 1 October 1993
- journal article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 129 (4), 461-464
- https://doi.org/10.1111/j.1365-2133.1993.tb03178.x
Abstract
Two patients suffering from pemphigus vulgaris were found to have nail dystrophies which antedated the onset of mucocutaneous lesions by many years. The nail changes improved substantially on treatment of the bullous disease. One patient had nail matrix histology consistent with pemphigus, and both had positive direct immunofluorescence with intercellular IgG in the matrix epithelium, as well as at other body sites. We propose that dystrophic nails, as a non-specific indicator of autoimmune disease, are a genuine and relevant finding in pemphigusKeywords
This publication has 15 references indexed in Scilit:
- Spongiotic trachyonychiaArchives of Dermatology, 1991
- The nail fold in pemphigus vulgarisArchives of Dermatology, 1990
- Idiopathic Atrophy of the NailsThe American Journal of Dermatopathology, 1988
- Nail abnormalities and autoimmunityJournal of the American Academy of Dermatology, 1988
- Immunofluorescence of the Nail Bed in PemphigoidThe American Journal of Dermatopathology, 1987
- Is childhood idiopathic atrophy of the nails due to lichen planus?British Journal of Dermatology, 1987
- Onychomadesis associated with pemphigus vulgarisArchives of Dermatology, 1981
- Twenty-nail dystrophy of childhoodArchives of Dermatology, 1977
- Three-year observation of a myasthenic syndrome concurrent with other autoimmune syndromes in a patient with thymomaJournal of the Neurological Sciences, 1969
- IDIOPATHIC ATROPHY OF THE NAILSBritish Journal of Dermatology, 1969