Parasite adaptation to locally common host genotypes
Top Cited Papers
- 1 June 2000
- journal article
- letter
- Published by Springer Science and Business Media LLC in Nature
- Vol. 405 (6787), 679-681
- https://doi.org/10.1038/35015069
Abstract
According to the Red Queen hypothesis—which states that interactions among species (such as hosts and parasites) lead to constant natural selection for adaptation and counter-adaptation—the disproportionate evolutionary success of parasites on common host genotypes leads to correlated selection for sexual reproduction1,2,3,4,5,6,7,8 and local adaptation by the parasite population9,10,11,12,13,14. Here we determined whether local adaptation is due to disproportionate infection of common host genotypes, and, if so, whether infection of common host genotypes is due to commonness per se, or some other aspect of these genotypes. In a reciprocal cross-inoculation experiment parasites occupying the same geographical area (sympatric) infected locally common host genotypes significantly more often than rare host genotypes, whereas parasites occupying separate geographical areas (allopatric) showed no such significant difference. A mixed source of parasites (containing F1 hybrids) also showed no difference in infection between rare and common host genotypes. These results show that local adaptation results from parasite tracking of locally common host genotypes, and, as such, a necessary condition of the Red Queen hypothesis is met.Keywords
This publication has 15 references indexed in Scilit:
- The Red Queen and Fluctuating Epistasis: A Population Genetic Analysis of Antagonistic CoevolutionThe American Naturalist, 1999
- Migration, Virulence, and the Geographic Mosaic of Adaptation by ParasitesThe American Naturalist, 1999
- Local adaptation and gene-for-gene coevolution in a metapopulation modelProceedings Of The Royal Society B-Biological Sciences, 1996
- Diverse, endemic and polyphyletic clones in mixed populations of a freshwater snail (Potamopyrgus antipodarum)Journal of Evolutionary Biology, 1995
- Preserving genes: a model of the maintenance of genetic variation in a metapopulation under frequency-dependent selectionGenetics Research, 1995
- Virulence and Local Adaptation of a Horizontally Transmitted ParasiteScience, 1994
- Parasitism, mutation accumulation and the maintenance of sexNature, 1994
- Antagonistic co-evolution and the evolution of genotypic randomizationJournal of Theoretical Biology, 1989
- Sex versus Non-Sex versus ParasiteOikos, 1980
- Sex and polymorphism as strategies in host-pathogen interactionsJournal of Theoretical Biology, 1980