Laryngopharyngeal reflux: Current concepts in pathophysiology, diagnosis, and treatment
- 1 January 2008
- journal article
- research article
- Published by Taylor & Francis Ltd in International Journal of Speech-Language Pathology
- Vol. 10 (4), 245-253
- https://doi.org/10.1080/17549500701862287
Abstract
Laryngopharyngeal reflux (LPR) is the backflow of gastric contents into the pharynx and larynx. The diagnosis of LPR is primarily based on symptoms, including dysphonia, dysphagia, globus, throat-clearing, and post-nasal drip. The gold standard for diagnosis is dual-probe 24-hour pH testing with the upper probe positioned above the upper oesophageal sphincter. Treatment may require 3 months or more of twice-daily proton pump inhibitors along with lifestyle modifications. This review details the pathophysiology, symptoms, findings, treatment, and current controversies in LPR.This publication has 66 references indexed in Scilit:
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