This study used the organizational affiliations of authors of published research to investigate interdisciplinary collaboration, a topic of increasing interest for both researchers and science policy-makers. It found that the amount of interdisciplinary collaboration research has steadily increased over a 20-year period. A journal's quality is positively correlated with the proportion of interdisciplinary papers it contains. However, there is insufficient evidence to support the belief that this type of research is, in general, of higher quality. The study also determined disciplines that collaborate most with the library and information science field.