Modern Radiotherapy as Part of Combined Modality Treatment in Locally Advanced Non-Small Cell Lung Cancer: Present Status and Future Prospects
- 1 June 2008
- journal article
- review article
- Published by Oxford University Press (OUP) in The Oncologist
- Vol. 13 (6), 700-708
- https://doi.org/10.1634/theoncologist.2007-0196
Abstract
Learning Objectives: After completing this course, the reader will be able to: Employ the current standard of care for stage III NSCLC.Balance the relative merits and risks of IMRT in this disease and position its indication.Advocate the need for further research for improvement in this field. CME This article is available for continuing medical education credit at CME.TheOncologist.com Locally advanced stages account for approximately one third of the incident presentations of non-small cell lung cancer (NSCLC). Optimal treatment in selected patients consists of an integration of chemotherapy and radiation therapy. Both modalities have seen numerous advances in the last decade. This article reviews the current status and outcome of treatment in stage III NSCLC, with special emphasis on the role of novel techniques in radiation treatment, including intensity-modulated radiation therapy. The obstacles for improving local control are identified and the technical progress that aims at removing these obstacles is addressed.Keywords
This publication has 54 references indexed in Scilit:
- Noninvasive Staging of Non-small Cell Lung CancerChest, 2007
- A1-05: Concomitant radio-chemotherapy (RT-CT) versus sequential RT-CT in locally advanced non-small cell lung cancer (NSCLC): A meta-analysis using individual patient data (IPD) from randomised clinical trials (RCTs)Journal of Thoracic Oncology, 2007
- Randomized Controlled Trial of Resection Versus Radiotherapy After Induction Chemotherapy in Stage IIIA-N2 Non-Small-Cell Lung CancerJNCI Journal of the National Cancer Institute, 2007
- Scalpels, Beams, Drugs, and Dreams: Challenges of Stage IIIA-N2 Non-Small-Cell Lung CancerJNCI Journal of the National Cancer Institute, 2007
- Cancer Statistics, 2007CA: A Cancer Journal for Clinicians, 2007
- Endoscopic Ultrasound–Guided Fine-Needle Aspiration in the Diagnosis and Staging of Lung Cancer and Its Impact on Surgical StagingJournal of Clinical Oncology, 2005
- Esophageal Endoscopic Ultrasound With Fine-Needle Aspiration With an On-site CytopathologistChest, 2005
- CT-based definition of thoracic lymph node stations: An atlas from the University of MichiganInternational Journal of Radiation Oncology*Biology*Physics, 2005
- Revisions in the International System for Staging Lung CancerChest, 1997
- Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trialsBMJ, 1995