Abdominal Lymphadenopathy Detected by Ultrasonography in HIV-1 Infection: Prevalence and Significance
- 1 January 1993
- journal article
- research article
- Published by Informa UK Limited in Scandinavian Journal of Infectious Diseases
- Vol. 25 (2), 221-225
- https://doi.org/10.3109/00365549309008488
Abstract
By using abdominal ultrasonography (UlS), deep nodes were detected in 41 of 85 (48%) HIV-1 positive subjects, most of them heroin addicts, but in none of 85 healthy HIV-negative controls. Computerized tomography, performed in 10 cases of lymphadenopathy, invariably confirmed the UlS findings. Prevalence [asymptomatic carriers: 8/15 (53%); PGL patients: 8/18 (44%); ARC: 13/27 (48%); AIDS: 12/25 (48%)], number, size, and site of deep nodes were comparable among the different CDC groups. No correlation was found between abdominal and superficial lymphadenopathy. Median serum concentrations of gammaglobulins (g/dl) and IgG (mg/dl) were higher in patients with than without deep nodes (2.25 vs 1.87 and 2540 vs 1900, respectively) (p < 0.01) as well as in cases with than without superficial nodes (2.15 vs 1.80 and 2340 vs 1941, respectively) (p < 0.05). Abdominal lymphadenopathy occurred during all stages of HIV infection even in asymptomatic carriers: this should be considered in the differential diagnosis of UlS-detected deep nodes. Enlargement of either deep or superficial nodes seems to reflect a state of polyclonal B cell activation.Keywords
This publication has 14 references indexed in Scilit:
- Prevalence and Significance of Abdominal Lymphadenopathy in Patients with Chronic Liver DiseaseJournal of Clinical Gastroenterology, 1990
- An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B HepatitisScience, 1989
- Lymphadenopathy in chronic active hepatitis: CT observationsAmerican Journal of Roentgenology, 1988
- Abdominal lymphadenopathy in benign diseases: CT detection.Radiology, 1987
- Classification System for Human T-Lymphotropic Virus Type III/ Lymphadenopathy-Associated Virus InfectionsAnnals of Internal Medicine, 1986
- AIDS-related lymphomas: evaluation by abdominal CT.Radiology, 1986
- Abdominal tuberculosis: CT evaluation.Radiology, 1985
- Abdominal lymphadenopathy in intravenous drug addicts: sonographic features and clinical significanceAmerican Journal of Roentgenology, 1985
- Burkitt Lymphoma in Acquired Immune Deficiency SyndromeJournal of Computer Assisted Tomography, 1984
- Kaposi sarcoma and lymphadenopathy syndrome: limitations of abdominal CT in acquired immunodeficiency syndrome.Radiology, 1984