A Bioartificial Liver--State of the Art
- 8 February 2002
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 295 (5557), 1005-1009
- https://doi.org/10.1126/science.1068660
Abstract
End-stage liver disease is treated by liver transplantation, but donor organ shortages remain a serious problem. This has prompted the design of bioartificial liver devices to “bridge” patients until they either recover or receive a liver transplant. In these devices, patient plasma is circulated extracorporeally through a bioreactor that houses liver cells (hepatocytes) sandwiched between artificial plates or capillaries.Keywords
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