Cross-trienamines in Asymmetric Organocatalysis
Open Access
- 30 July 2012
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 134 (31), 12943-12946
- https://doi.org/10.1021/ja3068269
Abstract
Cross-conjugated trienamines are introduced as a new concept in asymmetric organocatalysis. These intermediates are applied in highly enantioselective Diels–Alder and addition reactions, providing functionalized bicyclo[2.2.2]octane compounds and γ′-addition products, respectively. The nature of the transformations and the intermediates involved are investigated by computational calculations and NMR analysis.Keywords
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