Low sensitivity of a urine LAM-ELISA in the diagnosis of pulmonary tuberculosis
Open Access
- 28 August 2009
- journal article
- research article
- Published by Springer Science and Business Media LLC in BMC Infectious Diseases
- Vol. 9 (1), 141
- https://doi.org/10.1186/1471-2334-9-141
Abstract
The development and evaluation of rapid and accurate new diagnostic tools is essential to improve tuberculosis (TB) control in developing countries. In a previous study, the first release of a urine LAM-ELISA by Chemogen (Portland, USA) has been evaluated with a promising sensitivity and specificity for the diagnosis of pulmonary TB. In the present study, the now commercially available assay has been clinically assessed regarding its diagnostic value alone and in combination with clinical co-factors.Keywords
This publication has 36 references indexed in Scilit:
- Clinical Diagnostic Utility of IP-10 and LAM Antigen Levels for the Diagnosis of Tuberculous Pleural Effusions in a High Burden SettingPLOS ONE, 2009
- Facing the Crisis: Improving the Diagnosis of Tuberculosis in the HIV EraThe Journal of Infectious Diseases, 2007
- Progress towards improved tuberculosis diagnostics for developing countriesThe Lancet, 2006
- Easy SAS Calculations for Risk or Prevalence Ratios and DifferencesAmerican Journal of Epidemiology, 2005
- Meta-Analysis of BACTEC MGIT 960 and BACTEC 460 TB, with or without Solid Media, for Detection of MycobacteriaJournal of Clinical Microbiology, 2004
- Thirteen years HIV-1 sentinel surveillance and indicators for behavioural change suggest impact of programme activities in south-west TanzaniaAIDS, 2004
- Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratioBMC Medical Research Methodology, 2003
- Immunocytochemical Method for Early Laboratory Diagnosis of Tuberculous MeningitisClinical and Vaccine Immunology, 2002
- Diagnostic Evaluation of Urinary Lipoarabinomannan at an Ethiopian Tuberculosis CentreScandinavian Journal of Infectious Diseases, 2001
- Improved detection of mycobacterial antigens in clinical specimens by combined enzyme-linked immunosorbent assaysDiagnostic Microbiology and Infectious Disease, 1993