In Vitro Response of Blastocystis hominis to Antiprotozoal Drugs
- 1 May 1983
- journal article
- research article
- Published by Wiley in The Journal of Protozoology
- Vol. 30 (2), 332-334
- https://doi.org/10.1111/j.1550-7408.1983.tb02925.x
Abstract
Ten antiprotozoal drugs were tested in vitro against four axenic strains of the intestinal parasite Blastocystis hominis. Inhibitory drugs in order of effectiveness were emetine, metronidazole, furazolidone, trimethoprim sulfamethoxazole, 5-chloro-8-hydroxy-7-iodo-quinoline (Entero-Vioform), and pentamidine. Moderately inhibitory were two quinolines other than iodochlorhydroxquin. These were chloroquine and 5,7-diiodo-8-hydroxy-quinoline (Floraquin). Diloxanide furoate was not inhibitory. Paromomycin and other antibiotics were not inhibitory. Entero-Vioform and metronidazole have been effective in human and higher primate diarrhea caused by B. hominis.Keywords
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