Current incidence and outcome of the acute respiratory distress syndrome
Top Cited Papers
- 1 February 2016
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Current Opinion in Critical Care
- Vol. 22 (1), 1-6
- https://doi.org/10.1097/mcc.0000000000000266
Abstract
This article discusses recently published articles reporting the incidence and outcome of patients with the acute respiratory distress syndrome (ARDS). This is a difficult task since there is a marked variability regarding the methodology of the few, large epidemiological, and observational studies on ARDS. The review will mainly focus on publications from the past 18 months. We have reviewed new epidemiological studies reporting population-based incidence of ARDS. Also, we have reviewed the data on survival reported in observational and randomized controlled trials, discussed how the current ARDS definition modifies the true incidence of ARDS, and briefly mentioned recent approaches that appear to improve ARDS outcome. On the basis of current evidence, it seems that the incidence and overall hospital mortality of ARDS has not changed substantially in the last decade. Independent of the definition used for identification of ARDS patients, reported population-based incidence of ARDS is an order of magnitude lower in Europe than in the USA. Current hospital mortality of combined moderate and severe ARDS reported in observational studies is greater than 40%.Keywords
This publication has 26 references indexed in Scilit:
- Assessment of PaO2/FiO2 for stratification of patients with moderate and severe acute respiratory distress syndromeBMJ Open, 2015
- Incidence and outcome of acute lung injury and acute respiratory distress syndrome in the surgical intensive care unitIndian Journal of Critical Care Medicine, 2014
- Clinical trials in patients with the acute respiratory distress syndrome: Burn after readingIntensive Care Medicine, 2014
- A universal definition of ARDS: the PaO2/FiO2 ratio under a standard ventilatory setting—a prospective, multicenter validation studyIntensive Care Medicine, 2013
- Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010The Lancet, 2012
- The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilationIntensive Care Medicine, 2011
- Eight-Year Trend of Acute Respiratory Distress SyndromeAmerican Journal of Respiratory and Critical Care Medicine, 2011
- Association Between Time of Admission to the ICU and MortalitySocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 2010
- The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.American Journal of Respiratory and Critical Care Medicine, 1994
- ACUTE RESPIRATORY DISTRESS IN ADULTSThe Lancet, 1967