Genetic analysis workshop II: Sib pair screening tests for linkage
- 1 January 1984
- journal article
- research article
- Published by Wiley in Genetic Epidemiology
- Vol. 1 (2), 175-178
- https://doi.org/10.1002/gepi.1370010210
Abstract
For each marker locus and for every pair of sibs with data available in the 1983 workshop data, the proportion of genes identical by descent was estimated. The mean proportions were compared between concordant and discordant sib pairs, and the mean proportion for concordantly affected pairs was compared with one half. Together with standard tests of association, these were found to be sensitive screening tests for linkage.Keywords
This publication has 3 references indexed in Scilit:
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- Possible linkage relationships between certain blood groups and schizophrenia or other psychosesBehavior Genetics, 1973
- The investigation of linkage between a quantitative trait and a marker locusBehavior Genetics, 1972