Solitary Fibrous Tumor of the Pleura
Top Cited Papers
Open Access
- 1 October 2006
- journal article
- review article
- Published by SAGE Publications in Cancer Control
- Vol. 13 (4), 264-269
- https://doi.org/10.1177/107327480601300403
Abstract
The solitary fibrous tumor of the pleura (SFTP) is a rare primary tumor arising from mesenchymal cells in the areolar tissue subjacent to the mesothelial-lined pleura. Only about 800 cases have been reported in the medical literature. The tumor appears to be unrelated to malignant pleural mesothelioma, the most common primary tumor of the pleura. In just over half of these cases, the neoplasm presents as an asymptomatic mass, is often quite large, and is benign in 78% to 88% of patients. The initial evaluation and diagnosis, tumor classification, surgical treatment, results of therapy, and long-term prognosis are reviewed, based on a selective review of the literature from MEDLINE beginning 1980. Complete en bloc surgical resection is the preferred treatment of benign and malignant varieties of the tumor. The pedunculated tumors attached to the visceral pleura can be effectively treated with a wedge resection of lung. Sessile tumors arising on the lung require a larger lung resection. Sessile tumors on the chest wall require wide local excision, often with chest wall resection because of their propensity for local recurrence. Adjuvant therapy remains controversial in SFTP. Benign SFTP has a high cure rate and an 8% local recurrence rate that is usually amenable to curative re-excision. Malignant SFTP, especially the more common sessile type, has a 63% recurrence rate even with complete resection. The majority of patients with recurrent disease die of the tumor within 2 years. Nevertheless, the overall long-term cure rate for all patients is 88% to 92%.Keywords
This publication has 19 references indexed in Scilit:
- Familial Solitary Fibrous Tumor of the PleuraSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 2005
- Solitary Fibrous Tumors of the Pleura: Surgical Outcome and Clinical CourseThe Annals of Thoracic Surgery, 2005
- From the Archives of the AFIPRadioGraphics, 2003
- Malignant solitary fibrous tumor of the pleura: report of a case with cytogenetic analysisVirchows Archiv, 2003
- Solitary fibrous tumors of the pleuraThe Annals of Thoracic Surgery, 2002
- Multimodality treatment of diffuse malignant pleural mesotheliomaSeminars in Oncology, 2002
- Solitary fibrous tumour — everywhere, and a diagnosis in vogueHistopathology, 1997
- Localized Benign and Malignant Fibrous Tumors of the PleuraThe American Journal of Surgical Pathology, 1989
- Solitary fibrous tumors of the pleura: Eight new cases and review of 360 cases in the literatureCancer, 1981
- Localized mesothelioma of the pleuraThe Journal of Thoracic and Cardiovascular Surgery, 1978