Function in Elderly Cancer Survivors Depends on Comorbidities
Open Access
- 1 December 2003
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
- Vol. 58 (12), M1119-M1124
- https://doi.org/10.1093/gerona/58.12.m1119
Abstract
Background. Factors associated with functional status in elderly cancer survivors, in particular, comorbidity, have been inadequately studied. Methods. Of 4162 participants aged 65 and older enrolled in the Duke Established Populations for Epidemiologic Studies of the Elderly study in 1986, 376 of the participants self-reported a diagnosis of cancer. Participants were divided into 2 comorbidity groups and 4 cancer groups. Cancer groups included 132 participants diagnosed 0–4 years ago, 117 diagnosed 5–15 years ago, 127 diagnosed >15 years ago, and 3784 participants who had never been diagnosed with cancer. Comorbidity (self-reported stroke, diabetes, hypertension, and myocardial infarction) was classified as presence of 1 or no comorbidities (n = 3089) or 2 or more comorbidities (n = 1073). Function was assessed by Katz Activities of Daily Living, Rosow-Breslau, Nagi, and Instrumental Activities of Daily Living scales at the time of interview. Results. In a two-way analysis of covariance model of comorbidity and cancer group controlling for age, race, sex, education, marital status, depression, and cognitive status, duration of cancer survivorship does not influence most measures of function. In the subset of 376 cancer survivors, comorbidity significantly correlates with the functional status of these older cancer survivors (Conclusions. In the older cancer survivor, regardless of duration following diagnosis, the presence of comorbidity rather than the history of cancer per se correlates with impaired functional status.Keywords
This publication has 25 references indexed in Scilit:
- Primary Care for Survivors of Breast CancerThe New England Journal of Medicine, 2000
- Association of Comorbidity with Disability in Older WomenJournal of Clinical Epidemiology, 1999
- Validity of self-reported Cancers in a Propsective Cohort Study in Comparison with Data from State Cancer RegistriesAmerican Journal of Epidemiology, 1998
- The CES-D ScaleApplied Psychological Measurement, 1977
- A Measure of Primary Sociobiological FunctionsInternational Journal of Health Services, 1976
- Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily LivingThe Gerontologist, 1969
- A Guttman Health Scale for the AgedJournal of Gerontology, 1966
- Studies of Illness in the AgedJAMA, 1963
- Appraisal of methods for the study of chemotherapy of cancer in man: Comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramideJournal of Chronic Diseases, 1960
- The use of the nitrogen mustards in the palliative treatment of carcinoma.With particular reference to bronchogenic carcinomaCancer, 1948