Mechanism of action and antitumor activity of (S)-10-(2,6-dimethyl-4-pyridinyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyridol [1,2,3-de]-[1,4]benzothiazine-6-carboxylic acid (WIN 58161)
- 29 June 1995
- journal article
- Published by Elsevier BV in Biochemical Pharmacology
- Vol. 50 (1), 111-122
- https://doi.org/10.1016/0006-2952(95)00016-s
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine groupAntimicrobial Agents and Chemotherapy, 1992
- Significance of the methyl group on the oxazine ring of ofloxacin derivatives in the inhibition of bacterial and mammalian type II topoisomerasesAntimicrobial Agents and Chemotherapy, 1991
- Inhibitors of DNA gyrasePharmacology & Therapeutics, 1989
- Inhibitory effects of quinolones on DNA gyrase of Escherichia coli and topoisomerase II of fetal calf thymusAntimicrobial Agents and Chemotherapy, 1989
- Use of in vitro topoisomerase II assays for studying quinolone antibacterial agentsAntimicrobial Agents and Chemotherapy, 1989
- DNA TOPOISOMERASE POISONS AS ANTITUMOR DRUGSAnnual Review of Biochemistry, 1989
- Inhibitors of DNA topoisomerasesBiochemistry, 1988
- DNA topoisomerase II: A primer on the enzyme and its unique role as a multidrug target in cancer chemotherapyPharmacology & Therapeutics, 1987
- Mechanistic Aspects of DNA TopoisomerasesAdvances in protein chemistry, 1986
- DNA TOPOISOMERASESAnnual Review of Biochemistry, 1985