Recurrent pleomorphic adenoma of the parotid gland: Analysis of 108 consecutive patients
- 11 June 2007
- journal article
- research article
- Published by Wiley in Head & Neck
- Vol. 29 (9), 822-828
- https://doi.org/10.1002/hed.20613
Abstract
Background Surgery for recurrent parotid pleomorphic adenoma is a challenging problem. Methods One hundred eight patients who underwent 134 reoperations for recurrent parotid pleomorphic adenoma (follow-up, 22 years) were evaluated for histopathologic features and risk factors for recurrence. Results The number of reoperations for tumor recurrence ranged from 1 to 10. Twenty-seven patients (25%) developed permanent facial nerve weakness. The risks for clinically evident rerecurrence after 1, 5, and 15 years were 16%, 42%, and 75%, respectively. Female sex, young age at initial treatment, and enucleation instead of parotidectomy for treatment of the first recurrence were significant risk factors for rerecurrence. The mean number of recurrent tumor nodules was 26. Conclusions Surgery for recurrent parotid pleomorphic adenoma has a high rate of facial nerve morbidity. The chance of rerecurrence is high. Extended parotidectomy seems to be the best approach for the reoperation to reduce the risk of rerecurrence. © 2007 Wiley Periodicals, Inc. Head Neck 2007Keywords
This publication has 28 references indexed in Scilit:
- Recurrent Pleomorphic Adenoma of the Parotid Gland: A Prospective Histopathological and Immunohistochemical StudyThe Laryngoscope, 2004
- Histopathology of Pleomorphic Adenoma in the Parotid Gland: A Prospective Unselected Series of 100 CasesThe Laryngoscope, 2001
- Recurrent salivary gland pleomorphic adenoma: etiology, management, and resultsCurrent Opinion in Otolaryngology & Head and Neck Surgery, 2001
- Surgical management of 246 previously untreated pleomorphic adenomas of the parotid glandBritish Journal of Surgery, 1997
- Total conservative parotidectomy for primary benign pleomorphic adenoma of the parotid gland: A 25‐year experience with 229 patientsThe Laryngoscope, 1994
- Relationship of intraoperative rupture of pleomorphic adenomas to recurrence: An 11‐25 year follow‐up studyHead & Neck, 1994
- Loyal capsular dissection of parotid pleomorphic adenomasInternational Journal of Oral & Maxillofacial Surgery, 1993
- Management of pleomorphic adenoma of the parotidBritish Journal of Surgery, 1988
- Treatment of parotid gland tumours by conservative parotidectomyBritish Journal of Surgery, 1986
- Recurrent mixed tumors of the parotid gland—results of surgical therapyThe Laryngoscope, 1978